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Life restored at every level
  • What is Cushing's syndrome?
  • Signs & Symptoms
  • Diagnosis
  • Treatment
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Disclaimer

This site is provided as an information service for owners of dogs who have been prescribed Vetoryl by their vet. Vetoryl is a prescription-only medicine, available only from your veterinary surgeon. Any questions about your dog should be directed to your veterinary practice. Vetoryl is a registered trademark of Dechra Limited.

Transformation through treatment

In every dog with Cushing’s syndrome there is an opportunity to bring back health and restore life. Through effective treatment it is possible to improve your dog’s quality of life and reduce the risk of your dog developing other, potentially life-threatening conditions for which treatment can be intensive and costly.

Cushing’s syndrome has a widespread, negative impact on your dog’s quality of life and if left untreated your dog runs a greater risk of serious conditions such as:

  • diabetes mellitus
  • high blood pressure
  • pancreatitis (inflammation of the pancreas)
  • infections of the kidneys and urinary tract
  • pulmonary thromboembolism (blood clots in the lung)

Management of Cushing’s syndrome

Although Cushing’s syndrome cannot be cured it can be successfully managed using medication allowing your dog’s health to be restored. 

Treatment 

Treatment of hyperadrenocorticism (HAC) may be achieved by surgery (adrenalectomy or trans-sphenoidal hypophysectomy), pituitary irradiation, or medical treatment. Surgery and radiotherapy are complicated procedures available only at a few specialty centers, therefore medical treatment is often the most practical and approachable treatment choice.  Trilostane is the only approved treatment available in Canada for both pituitary-dependent hyperadrenocorticism (PDH) and adrenal-dependent hyperadrenocorticism (ADH). Although the daily administration of trilostane does not offer a medical cure for Cushing’s syndrome, it may allow the disease to be managed successfully, enhancing the dog’s vitality and quality of life.

Use the personalised online logbook to help you keep track of your dog’s progress following treatment:

Go to your treatment log book

Your veterinarian will assess your dog’s response to treatment by:

Looking for improvement in clinical signs

In most cases you can expect to see a decrease in your dog’s appetite and the amount they drink within the first couple of weeks on treatment as well as an improvement in their level of energy. Other  symptoms may take 3 to 6 months to improve.

Performing blood tests

The results of routine blood tests and an ACTH stimulation test are used to assess the effectiveness of Vetoryl treatment at 10-14 days, 4 weeks, 12 weeks and every 3 months after starting treatment.

Pre-treatment

Pre-treatment

3 months of treatment

3 months of treatment

9 months of treatment

9 months of treatment

Photos © Carlos Melian

Monitoring your dog

Your dog should be closely monitored in the early stages of therapy so that the dose of Vetoryl can be adjusted to meet its specific needs. This also helps to minimise the risk of side-effects or complications that could be harmful to your dog.

If your dog develops any signs of illness while on Vetoryl including lethargy, vomiting, diarrhea and anorexia, stop treatment immediately and contact your  veterinarian as soon as possible.

When your veterinarian is happy with your dog’s progress, it is strongly recommended that you visit your veterinarian every 3 months for regular monitoring so that any dose adjustments can be made as required.

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This site is provided as an information service for veterinary professionals and the owners of dogs who have been prescribed Vetoryl by their vet. Vetoryl is a prescription-only medicine, available only from your veterinarian. Any questions about your dog should be directed to your veterinary practice. Vetoryl is a registered trademark of Dechra Limited.

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