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Life restored at every level
  • What is Cushing's syndrome?
  • Signs & Symptoms
  • Diagnosis
  • Treatment
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This site is provided as an information service for owners of dogs who have been prescribed Vetoryl by their vet. Vetoryl is a prescription-only medicine, available only from your veterinary surgeon. Any questions about your dog should be directed to your veterinary practice. Vetoryl is a registered trademark of Dechra Limited.

Transformation through treatment

In every dog with Cushing’s syndrome there is an opportunity to bring back health and restore life. Through effective treatment it is possible to improve your dog’s quality of life and reduce the risk of your dog developing other, potentially life-threatening conditions for which treatment can be intensive and costly.

Cushing’s syndrome has a widespread, negative impact on your dog’s quality of life and if left untreated your dog runs a greater risk of serious conditions such as:

  • diabetes mellitus
  • high blood pressure
  • pancreatitis (inflammation of the pancreas)
  • infections of the kidneys and urinary tract
  • pulmonary thromboembolism (blood clots in the lung)

Management of Cushing’s syndrome

Although Cushing’s syndrome cannot be cured it can be successfully managed using medication allowing your dog’s health to be restored. Vetoryl® is the only licensed treatment for use in dogs. Vetoryl contains the active ingredient trilostane, a drug which reduces the production of cortisol by the adrenal glands.

Treatment with Vetoryl

Vetoryl has the power to restore life and vitality to your dog. This can have a positive effect on you and your family too. You can welcome back the animal you thought you’d lost to Cushing’s syndrome.

Once your dog has started treatment with Vetoryl, you should soon notice some marked improvements. It is important that you follow the instructions given by your veterinarian.Your dog will require a blood test 10 to 14 days after starting treatment to evaluate cortisol levels. If necessary your  veterinarian may have to adjust the dosage of Vetoryl.

Every dosage change should again be followed by a check-up after 10 to 14 days.

Use the personalised online logbook to help you keep track of your dog’s progress following treatment with Vetoryl:

Go to your treatment log book

Your veterinarian will assess your dog’s response to Vetoryl treatment by:

Looking for improvement in clinical signs

In most cases you can expect to see a decrease in your dog’s appetite and the amount they drink within the first couple of weeks on treatment as well as an improvement in their level of energy. Other  symptoms may take 3 to 6 months to improve.

Performing blood tests

The results of routine blood tests and an ACTH stimulation test are used to assess the effectiveness of Vetoryl treatment at 10-14 days, 4 weeks, 12 weeks and every 3 months after starting treatment.

Pre-treatment

Pre-treatment

3 months of treatment

3 months of treatment

9 months of treatment

9 months of treatment

Photos © Carlos Melian

Monitoring your dog

Your dog should be closely monitored in the early stages of therapy so that the dose of Vetoryl can be adjusted to meet its specific needs. This also helps to minimise the risk of side-effects or complications that could be harmful to your dog.

If your dog develops any signs of illness while on Vetoryl including lethargy, vomiting, diarrhea and anorexia, stop treatment immediately and contact your  veterinarian as soon as possible.

When your veterinarian is happy with your dog’s progress, it is strongly recommended that you visit your veterinarian every 3 months for regular monitoring so that any dose adjustments can be made as required.

Do’s and Don’ts for using Vetoryl

Do:

  • Give Vetoryl capsules in the morning with food, so they can be easily absorbed. This also allows your veterinarian to carry out monitoring tests at the appropriate time of day.
  • Take your dog back to your veterinarian for regular monitoring.
  • Note your dog’s weight, water consumption, appetite and frequency of urination so you can monitor its improvement once treatment starts. Contact your veterinarian if you have any concerns.
  • Contact your veterinarian immediately if your dog stops eating, drinking or urinating or becomes unwell while on Vetoryl.
  • Wash your hands after using Vetoryl.
  • Book follow up appointments with your veterinarian every three months so that progress can be assessed.
  • You might like to consider taking a photo before you start treatment - improvements such as hair regrowth or the loss of a pot-belly occur gradually so are less noticeable on a daily basis.
  • Ensure you continue giving your dog the prescribed dose of Vetoryl even if you notice dramatic physical improvements. Vetoryl will curb the excesses associated with the overproduction of cortisol but it will not cure the disease.
  • Monitoring is important and regular checks performed by your veterinarian will ensure your dog continues to get the best possible care.

Don't:

  • Split the capsules.
  • Give a double dose if you have forgotten a dose before. Consult your veterinarian.
  • Handle Vetoryl capsules if you are pregnant, or planning to become pregnant.
  • Change the daily dosage without consulting your veterinarian.
  • Stop administering the prescribed dosage of Vetoryl because you notice an improvement in the condition of your dog.

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This site is provided as an information service for veterinary professionals and the owners of dogs who have been prescribed Vetoryl by their vet. Vetoryl is a prescription-only medicine, available only from your veterinarian. Any questions about your dog should be directed to your veterinary practice. Vetoryl is a registered trademark of Dechra Limited.

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